A novel antagonistic role of natural compound icariin on neurotoxicity of amyloid β peptide
نویسندگان
چکیده
منابع مشابه
A novel antagonistic role of natural compound icariin on neurotoxicity of amyloid β peptide
BACKGROUND & OBJECTIVES Amyloid β-peptide (Aβ) has been shown to be responsible for senile plaque formation and cell damage in Alzheimer's disease (AD). This study was aimed to explore the role of natural compound icariin on the aggregation and the cytotoxicity of Aβ in vitro. METHODS Thioflavin T (ThT) fluorescence assay and transmission electron microscopy (TEM) imaging were done to determi...
متن کاملthe role of semantic and communicative translation on reading comprehension of scientific texts
the following null hypothesis was proposed: h : there is no significant difference between the use of semantically or communicatively translates scientific texts. to test the null hypothesis, a number of procedures were taken first, two passages were selected form soyrcebooks of food and nutrition industry and gardening deciplines. each, in turn, was following by a number of comprehension quest...
15 صفحه اولwuthering heights and the concept of marality/a sociological study of the novel
to discuss my point, i have collected quite a number of articles, anthologies, and books about "wuthering heights" applying various ideas and theories to this fantastic story. hence, i have come to believe that gadamer and jauss are rightful when they claim that "the individaul human mind is the center and origin of all meaning," 3 that reading literature is a reader-oriented activity, that it ...
15 صفحه اولeffect of amyloid β- peptide on passive avoidance learning in rats: a behavioral study
conclusions these data suggest that single bilateral microinjection of aβ (25-35) could impair memory and can be used as an ad model in wistar rats. results the results showed that aβ (25-35) significantly impaired both step-through latency and time in dark compartment in the passive avoidance task. background alzheimer's disease (ad) is the most common form of dementia that leads to neurotoxic...
متن کاملMespilus germanica leaves flavonoids improve passive avoidance memory and apoptosis in a rat model of amyloid-β neurotoxicity
Introduction: Alzheimer’s disease (AD) is a common progressive, neurodegenerative disorder with no preventive or curative therapy until now. Use of natural products as an important source of neuroprotective flavonoids against AD has been considered recently. In this study, the effect of Mespilus germanica leaves (MGL) flavonoids treatment on memory dysfunction and apoptosis in the amyloid beta ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Indian Journal of Medical Research
سال: 2015
ISSN: 0971-5916
DOI: 10.4103/0971-5916.164254